Disposable isolation gowns are essential PPE garments worn by healthcare professionals to protect against the transfer of microorganisms, bodily fluids, and particulate matter. These gowns are particularly important in infection-prone settings such as operating rooms, isolation wards, and diagnostic labs where exposure risk is high. Manufactured from lightweight, fluid-resistant materials like SMS (spunbond-meltblown-spunbond) fabric or polyethylene-coated polypropylene, these gowns offer a reliable barrier without compromising comfort or mobility. They come in both open-back and full-back designs, typically secured with neck ties and waist belts, and feature knit or elastic cuffs for a secure fit over gloves. Isolation gowns are used during patient examinations, handling of infectious waste, surgical procedures, and intensive care treatments. They are designed for single use and should be properly discarded after exposure to contaminants to prevent cross-infection. Color-coded options are sometimes available to distinguish between departments or procedural categories. These gowns comply with international standards (such as AAMI Level 1–4) indicating their protective capability based on liquid barrier performance. Available in multiple sizes, they accommodate all body types and can be folded flat for compact storage in PPE stations. Whether in pandemic response or routine infection control, disposable isolation gowns provide critical protection and enhance patient and caregiver safety in clinical and laboratory settings.